Employment

• 1982-86 Research Assistant, Shanghai Institute of Plant Physiology, Academica Sinica, Shanghai, China
• 1986-93 Research Associate, Boston Biomedical Research Institute, Boston, MA
• 1933-95 Research Fellow, Deaconess Hospital, Harvard Medical School, Boston, MA
• 1995-2000 Research Associate, Brigham and Women’s Hospital, Boston, MA
• 2000- Research Specialist, Brigham and Women’s Hospital, Boston, MA

Publications

• Zhang Y, Cao Q, Li Z, Cui D. Preparation of [B23-D-alanine]des-(B25-B30)-hexapeptide-insulin by a combination of enzymic and non-enzymic synthesis. Biochem J 1983; 215:697-699.
• Zhu J, Li Z, Wang L, Shen S. Temperature sensitivity of a nif A-like gene in Enterobacter cloacae. J Bacteriology 1986; 357-359.
• Jiang S, Yu G, Li Z, Hong J. Genetic evidence for modulation of the activator by two regulatory proteins involved in the exogenous induction of phosphoglycerate transport in salmonella typhimurium. J Bacteriology 1988; 4304-4308.
• Sacks DB, Lopez MM, Li Z, Kosk-Kosicka D. Analysis of phosphorylation and mutation of tyrosine residues of calmodulin on its activation of the erythrocyte Ca2+-transporting ATPase. Eur J Biochem 1996; 239:98-104.
• Ho YD, Joyal JL, Li Z, Sacks DB. IQGAP1 integrates Ca2+/calmodulin and Cdc42 signaling. J Biol Chem 1999; 274:464-470.
• Li Z, Kim SH, Higgins JM, Brenner MB, Sacks DB. IQGAP1 and calmodulin modulate E-cadherin function. J Biol Chem 1999; 274:37885-37892.
• Li Z, Joyal JL, Sacks DB. Binding of IRS proteins to calmodulin is enhanced in insulin resistance. Biochemistry 2000; 39:5089-5096.
• Kim SH, Li Z, Sacks DB. E-cadherin-mediated cell-cell attachment activates Cdc42. J Biol Chem 2000; 275:36999-37005.
• Li Z, Joyal JL, Sacks DB. Calmodulin enhances the stability of the estrogen receptor. J Biol Chem 2001; 276: 17354-17360.
• Sokol SY, Li Z, Sacks DB. The effect of IQGAP1 on Xenopus embryonic ectoderm requires Cdc42. J Biol Chem 2001; 276:48425-48430.
• Briggs MW, Li Z, Sacks DB. IQGAP1-mediated stimulation of transcriptional co-activation by b-catenin is modulated by calmodulin. J Biol Chem 2002; 277:7453-7465.
• Swart-Mataraza JM, Li Z, Sacks DB. IQGAP1 is a component of Cdc42 signalling to the cytoskeleton. J Biol Chem 2002; 277:24753-24763.
• Mataraza JM, Briggs MW, Li Z, Frank R, Sacks DB. Identification and characterization of the Cdc42-binding site of IQGAP1. Biochem Biophys Res Commun 2003; 305:315-321.
• Li L, Li Z, Sacks DB. Calmodulin regulates the transcriptional activity of estrogen receptors: selective inhibition of calmodulin function in subcellular compartments. J Biol Chem 2003; 278:1195-1200.
• Li Z, Sacks DB. Elucidation of the interaction of calmodulin with the IQ motifs of IQGAP1. J Biol Chem 2003; 278:4347-4352.