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***Click on the authors to view the abstract at the National Library of
Medicine's PubMed***
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Sacks DB, McDonald JM. Insulin-stimulated
phosphorylation of calmodulin by rat liver insulin receptor preparations.
J Biol Chem 1988; 263:2377-2383.
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Sacks DB, Fujita-Yamaguchi Y, Gale RD, McDonald JM.
Tyrosine-specific phosphorylation of calmodulin by the insulin receptor
kinase purified from human placenta. Biochem J 1989; 263:803-812.
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Fujita-Yamaguchi Y, Sacks DB, McDonald JM, Sahal D, Kathuria S.
Effect of basic polycations and proteins on purified insulin receptor.
Insulin-independent activation of the insulin receptor tyrosine-specific
protein kinase by poly(L-lysine). Biochem J 1989; 263:813-822.
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Sacks DB, Glenn KC, McDonald JM.
The carboxyl terminal segment of the c-Ki-ras 2 gene product mediates
insulin-stimulated phosphorylation of calmodulin and stimulates insulin-dependant
autophosphorylation of insulin receptor. Biochem Biophys Res Commun.
1989;161:399-405.
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Sacks DB, Porter SE, Ladenson JH, McDonald JM
. Monoclonal antibody to calmodulin: Development, characterization
and comparison with polyclonal anti-calmodulin antibodies. Anal
Biochem 1991; 194:369-377.
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Reddy GP, Reed WC, Sheehan EL, Sacks DB.
Calmodulin-specific monoclonal antibodies inhibit DNA replication in
mammalian cells. Biochemistry 1992; 31:10426-10430.
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Sacks DB, Davis HW, Sheehan EL, Williams JP, Garcia JG, McDonald JM.
Phosphorylation by casein kinase II alters the biological activity of
calmodulin. Biochem J 1992; 283:21-24.
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Sacks DB, Davis HW, Crimmins DL, McDonald JM.
Insulin-stimulated phosphorylation of calmodulin. Biochem J 1992;
286:211-216.
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Tanasijevic MJ, Myers MG Jr, Thoma RS, Crimmins DL, White MF, Sacks
DB . Phosphorylation of the insulin
receptor substrate IRS-1 by casein kinase II. J Biol Chem 1993;
268:18157-18166.
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Joyal JL, Sacks DB. Insulin-dependent
phosphorylation of calmodulin in rat hepatocytes. J Biol Chem
1994; 269:30039-30048.
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Sacks DB, Mazus B, Joyal JL.
The activity of calmodulin is altered by phosphorylation: modulation
of calmodulin function by the site of phosphate incorporation.
Biochem J 1995; 312:197-204.
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Joyal JL, Crimmins DL, Thoma RS, Sacks DB
. Identification of insulin-stimulated phosphorylation sites on
calmodulin. Biochemistry 1996; 35:6267-6275.
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Munshi HG, Burks DJ, Joyal JL, White MF, Sacks DB
. Ca2+
regulates calmodulin binding to IQ motifs in IRS-1. Biochemistry 1996;
35:15883-15889.
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Joyal JL, Annan RA, Ho YD, Huddleston ME, Carr SA, Hart MJ, Sacks DB
. Calmodulin modulates the interaction between IQGAP1 and Cdc42:
Identification of IQGAP1 by nanoelectro-spray tandem mass spectrometry.
J Biol Chem 1997; 272:15419-15425.
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Joyal JL, Burks DJ, Pons S, Matter WF, Vlahos CJ, White MF, Sacks DB
. Calmodulin activates phosphatidylinositol 3-kinase. J
Biol Chem 1997; 272:28183-28186.
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Ho YD, Joyal JL, Li Z, Sacks DB. IQGAP1
integrates Ca2+
/calmodulin and Cdc42 signaling. J Biol Chem 1999;274:464-470.
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Li Z, Kim SH, Higgins JM, Brenner MB, Sacks DB
. IQGAP1 and calmodulin modulate E-cadherin function. J
Biol Chem 1999; 274:37885-37892.
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Li Z, Joyal JL, Sacks DB. Binding
of IRS proteins to calmodulin is enhanced in insulin resistance.
Biochemistry 2000; 39:5089-5096.
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Kim SH, Li Z, Sacks DB. E-cadherin-mediated
cell-cell attachment activates Cdc42. J Biol Chem 2000; 275: 36999-37005.
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Li Z, Joyal JL, Sacks DB. Calmodulin enhances the stability
of the estrogen receptor. J Biol Chem. 2001;276:17354-60.
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Sokol SY, Li Z, Sacks DB. The effect of IQGAP1 on Xenopus
embryonic ectoderm requires Cdc42. J Biol Chem. 2001;276:48425-30.
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Briggs MW, Li Z, Sacks DB. IQGAP1-mediated stimulation of
transcriptional co-activation by beta-catenin is modulated by calmodulin.
J Biol Chem. 2002;277:7453-65.
- Swart-Mataraza
JM, Li Z, Sacks DB. IQGAP1 is a component of Cdc42 signaling to
the cytoskeleton. J Biol Chem 2002; 277:24753-24763.
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Li L, Li Z, Sacks DB. Calmodulin regulates the transcriptional activity
of estrogen receptors: selective inhibition of calmodulin function in
subcellular compartments. J Biol Chem 2003; 278:1195-1200.
- Li
Z, Sacks DB. Elucidation of the interaction of calmodulin with the
IQ motifs of IQGAP1. J Biol Chem 2003; 278:4347-4352.
- Mataraza
JM, Briggs MW, Li Z, Frank R, Sacks DB. Identification and characterization
of the Cdc42-binding site of IQGAP1. Biochem Biophys Res Commun 2003;
305:315-321.
- Briggs
MW, Sacks DB. IQGAP1 as signal integrator: Ca2+, calmodulin, Cdc42
and the cytoskeleton [Review]. FEBS Lett 2003; 542:7-11.
- Briggs
MW, Sacks DB. IQGAP proteins are integral components of cytoskeletal
regulation [Review]. EMBO Rep. 2003; 4:571-4.
- Mataraza
JM, Briggs MW, Li Z, Entwistle A, Ridley AJ, Sacks DB. IQGAP1 promotes
cell motility and invasion. J Biol Chem 2003; 278(42):41237-45.
- Roy
M, Li Z, Sacks DB.
IQGAP1 binds ERK2 and modulates its activity. J Biol Chem 2004; 279:17329-37.
- Li
Z, McNulty DE, Marler KJ, Lim L, Hall C, Annan RS, Sacks DB.
IQGAP1 promotes neurite outgrowth in a phosphorylation-dependent manner.
J Biol Chem 2005; 280:13871-8.
- Li
L, Li Z, Sacks DB. The transcriptional activity of estrogen receptor-alpha
is dependent on Ca2+/calmodulin. J Biol Chem. 2005; 280:13097-104.
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Ren JG, Li Z, Crimmins DL, Sacks DB. Self-association of IQGAP1:
characterization and functional sequelae. J Biol Chem 2005;280:34548-57.
- Roy
M, Li Z, Sacks DB. IQGAP1 is a scaffold for mitogen-activated protein
kinase signaling. Mol Cell Biol 2005;25:7940-52.
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Li L, Li Z, Howley PM, Sacks DB. E6AP and calmodulin reciprocally
regulate estrogen receptors stability. J Biol Chem 2006; 281(4):1978-85
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Brown MD, Sacks DB. IQGAP1 in cellular signaling: bridging the GAP. Trends
Cell Biol 2006; 16(5) 242-9;
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